John Negroponte entered the US diplomatic corps in 1960, when the War was on in Vietnam, he began his tour of duty in Saigon embassy in South Vietnam. From 1971 to 1973 he was the right hand of Henry Kissinger. From 1981 to 1985 he was the U.S. Ambassador to Honduras and his skills made him the man of «special missions» and thus the roles assigned to him always had a greater index of difficulty. During Reagan’s and Bush’s presidencies, Negroponte was the Deputy Assistant to the President for National Security Affairs. In 1997 he was expected to become Ambassador to Greece, but due to the tension in Honduras where he had served for many years he was considered appropriate to follow a different path in his career.

In his personal life, John Negroponte is married to Diana Mary Villiers and they have five adopted children! John, Alexandra, George, Sophia and Marina Negroponte, who appears early on to have chosen to march in the footsteps of her father, and she now works at the World Food Programme at the United Nations.