One of the 200 most prominent clinical investigators in the world
Achievements

One of the 200 most prominent clinical investigators in the world

George Chrousos is among the most cited clinical and basic investigators in the world in the fields of Clinical Medicine, Biology and Biochemistry and the highest cited clinical Endocrinologist and Pediatrician as his work has been cited over 50,000 times.

George Chrousos is professor and chairman of the Department of Pediatrics at the Athens University Medical School. Before returning to Greece he was a Clinical Professor of Pediatrics, Physiology and Biophysics at Georgetown University Medical School and Distinguished Visiting Scientist at the National Institute of Child Health and Human Development (NICHD). He was also for many years Section Chief, and later Branch Chief of the Pediatric and Reproductive Endocrinology Branch, NICHD.

Chrousos was born in Patra, Greece, attended the University of Athens Medical School and finished as the valedictorian of his class in 1975. He completed his doctorate thesis at the University of Athens, followed by a residency in Pediatrics at New York University Medical School, New York and a fellowship in Endocrinology, Metabolism and Diabetes at the Clinical Center of the National Institutes of Health, Bethesda, Maryland.

Dr. Chrousos was the first General Director of the Foundation of Biomedical Research of the Academy of Athens (2001–2002). He holds the UNESCO Chair on Adolescent Health Care and held the John Kluge Chair in Technology and Society, Library of Congress, Washington, D.C.

He is devoted to the integrative approach and thinking in medicine, and has performed seminal work in the stress research field mostly related to the hypothalamic-pituitary-adrenal (HPA) axis, a major branch of the stress system. His work has led to improved understanding of the physiology and pathophysiology of the stress response at the neuroendocrine, cellular and molecular levels.

He described the syndrome of glucocorticoid resistance as a disease of the glucocorticoid receptor and subsequently reported the majority of the kindred with this disorder in the world. Dr. Chrousos is recognized worldwide for his highly original work on the glucocorticoid signaling system, diseases of the HPA axis, such as Cushing’s syndrome, Addison’s disease, and congenital adrenal hyperplasia, the physiology of corticotropin-releasing hormone (CRH), the development of new CRH receptor antagonists, the hypersecretion of CRH in melancholic depression, anorexia nervosa and other stress-related disorders and for elucidating the differential diagnosis of depression-related Pseudocushing and Cushing Syndrome.

Chrousos has contributed immensely to the biomedical literature and his work has provided new insights into a spectrum of clinical conditions and disorders that transcend the limits of classical endocrinology, such as reproduction and pregnancy, inflammation, stress-immune interactions, surgical stress, sleep, and septic shock, as well as chronic complex disorders such as depression, eating disorders, asthma, metabolic syndrome and autoimmune-inflammatory diseases.

He has a record of over 16 full publications in the New England Journal of Medicine, with his highly cited review on “The Hypothalamic-Pituitary-Adrenal Axis and Immune-Mediated Inflammation”. He has also an outstanding record of over 1100 scientific papers, edited 29 books, including 2 popular electronic volumes and 2 encyclopaedias.
Dr. Chrousos has received the following awards : Fred Conrad Koch Award, The US Endocrine Society (2014), Honorary Professor, Warwick University, Coventry, UK (2013), UNICEF Award, National UNICEF Committee, Athens, Greece (2012), Albert Struyvenberg Medal, European Society of Clinical Investigation (2012), Constantine Moiras Award, Academy of Athens, Athens, Greece (2011), The Bodossaki Aristeion Prize, Bodossaki Foundation, Athens, Greece (2011), John Kluge Chair in Technology and Society, Library of Congress, Washington, D.C.(2011), Member, Academia Europaea, London, UK (2010), Member, Institute of Medicine, The National Academies, Washington, D.C. (2010), Philip S. Hench Memorial Lecture, American College of Rheumatology, Atlanta, GA. (2010), UNESCO Chair on Adolescent Health Care, University of Athens, Athens, Greece (2010), Mortimer B. Lipsett Memorial Lecture, NIH (2009), Geoffrey Harris Award, European Society of Endocrinology (2008), Lifetime Achievement Award of the International Society of Psychoneuroendocrinology (2004), Sir Edward Sharpey-Schafer Medal of the British Endocrine Societies (2002), Novera Herbert Spector Award of the International Society of Neuroimmunomodulation (1999), Hans Selye Award, Hans Selye Foundation (1997) and Richard Weitzman Award, The US Endocrine Society (1987).

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