Aiming at developing novel therapies for cancer and central nervous system diseases

Aiming at developing novel therapies for cancer and central nervous system diseases

Costas Arvanitis is an assistant Professor at the Georgia Institute of Technology. He is an expert in biomedical acoustics, instrumentation and control, medical devices, system identification, quantitative medical imaging and processing, numerical modeling, drug and gene delivery and cancer biology.

He was an Instructor at the Department of Radiology of the Brigham and Women’s Hospital of Harvard until July 2016.

Costas Arvanitis research is concentrated on understanding the biological effects of acoustically induced microbubble oscillations (acoustic cavitation) and their use to study complex biological systems, such as the neurovascular network and tumor microenvironment and develop novel therapies for the treatment of cancer and central nervous system diseases and disorders.

In 2002 he got his B.Sc. in Biomedical Engineering from the Technological Educational Institution of Athens and in 2005 he earned his M.Sc. in Medical Physics from the University of Patras in Greece. In 2008 Dr. Arvanitis completed his Ph.D. in Medical Physics from the University College London in the United Kingdom.

During his research fellowship from March 2010 to July 2014, Arvanitis engineered multi-modality and multi-scale approaches to characterize, control and map acoustic cavitation and shed light on the interactions of oscillating microbubbles with neurovascular networks, such as the blood brain barrier (BBB).

In collaboration with Prof. M. Livingstone, they have demonstrated the safety of FUS – induced BBB disruption by evaluating its impact on the visual and cognitive abilities on non-human primates. As a Postdoctoral Researcher (2007-2009), he developed ultrasound systems to study and optimize the ability of acoustic cavitation to noninvasively propel oncolytic adenoviruses deep into solid tumours.

Costas Arvanitis has published several original articles. In 2014 he received the Roberts Prize Award for the best article in the journal of Physics in Medicine and Biology. He is also the recipient of the National Institutes of Health (NIH) and National Institute of Biomedical Imaging and Bioengineering (NIBIB) K99/R00 Award.

Arvanitis has also given several invited talks at local laboratories and national and international conferences, mentored undergraduate and graduate students and given lectures, tutorials and laboratory demonstrations at undergraduate and graduate level at the University of Oxford and Harvard Medical School.