Discovered 2 new gene variations which increase the possibilities of breast cancer
Kyriaki Michailidou is a member of a large international research team that succeeded in discovering two new genetic variations that increase the chance for women to develop breast cancer.
Over 100.000 women, with and without breast cancer, had their DNA analyzed and they accomplished in finding that the two variants, rs10816625 and rs13294895, influence a gene known as KLF4, a gene thought to be involved in the control of cellular growth and division.
For women carrying the first variant they have 12% greater chance of developing breast cancer versus those without it and for women with the second variation a 9% greater risk.
Michailidou completed her BSc in Mathematics at the Aristotle University of Thessaloniki in Greece. Then she moved to the United Kingdom to get her MSc in Applied Statistics at the University of Oxford.
In 2009 she joined the Centre of Cancer Genetic Epidemiology group of the University of Cambridge as a statistician and in 2011 was working her PhD with the thesis title of “Genome-Wide Association studies in Breast Cancer”, supervised by Prof. Douglas Easton.
From 2012 she has written many publications about genetics and cancer.